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Life span pigmentation changes of the substantia nigra detected by neuromelanin‐sensitive MRI

Background: Neuromelanin is a pigment with strong iron‐chelating properties preferentially found in dopaminergic neurons of the substantia nigra pars compacta (SNpc). Parkinson's disease is characterized by pronounced, MRI‐detectable neuromelanin loss, but the neuroprotective or neurotoxic role...

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Detalles Bibliográficos
Autores principales: Xing, Yue, Sapuan, Abdul, Dineen, Rob A., Auer, Dorothee P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659388/
https://www.ncbi.nlm.nih.gov/pubmed/30423212
http://dx.doi.org/10.1002/mds.27502