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A New Use for an Old Drug: Carmofur Attenuates Lipopolysaccharide (LPS)-Induced Acute Lung Injury via Inhibition of FAAH and NAAA Activities

Acute lung injury (ALI), characterized by a severe inflammatory process, is a complex syndrome that can lead to multisystem organ failure. Fatty acid amide hydrolase (FAAH) and N-acylethanolamine acid amidase (NAAA) are two potential therapeutic targets for inflammation-related diseases. Herein, we...

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Detalles Bibliográficos
Autores principales: Wu, Kangni, Xiu, Yanghui, Zhou, Pan, Qiu, Yan, Li, Yuhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659393/
https://www.ncbi.nlm.nih.gov/pubmed/31379583
http://dx.doi.org/10.3389/fphar.2019.00818