Computational approaches: discovery of GTPase HRas as prospective drug target for 1,3-diazine scaffolds

Heterocyclic 1,3-diazine nucleus is a valuable pharmacophore in the field of medicinal chemistry and exhibit a wide spectrum of biological activities. PharmMapper, a robust online tool used for establishing the target proteins based on reverse pharmacophore mapping. PharmMapper study is carried out...

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Detalles Bibliográficos
Autores principales: Kumar, Sanjiv, Sharma, Deepika, Narasimhan, Balasubramanian, Ramasamy, Kalavathy, Shah, Syed Adnan Ali, Lim, Siong Meng, Mani, Vasudevan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659553/
https://www.ncbi.nlm.nih.gov/pubmed/31355369
http://dx.doi.org/10.1186/s13065-019-0613-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659553/
https://www.ncbi.nlm.nih.gov/pubmed/31355369
http://dx.doi.org/10.1186/s13065-019-0613-8

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