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Targeting metabolic driving and intermediate influx in lysine catabolism for high-level glutarate production

Various biosynthetic pathways have been designed to explore sustainable production of glutarate, an attractive C5 building block of polyesters and polyamides. However, its efficient production has not been achieved in Escherichia coli. Here, we use E. coli native lysine catabolic machinery for gluta...

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Detalles Bibliográficos
Autores principales: Li, Wenna, Ma, Lin, Shen, Xiaolin, Wang, Jia, Feng, Qi, Liu, Lexuan, Zheng, Guojun, Yan, Yajun, Sun, Xinxiao, Yuan, Qipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659618/
https://www.ncbi.nlm.nih.gov/pubmed/31350399
http://dx.doi.org/10.1038/s41467-019-11289-4