Regulation of antitumour CD8 T-cell immunity and checkpoint blockade immunotherapy by Neuropilin-1

Neuropilin-1 (Nrp-1) is a marker for murine CD4(+)FoxP3(+) regulatory T (Treg) cells, a subset of human CD4(+) Treg cells, and a population of CD8(+) T cells infiltrating certain solid tumours. However, whether Nrp-1 regulates tumour-specific CD8 T-cell responses is still unclear. Here we show that...

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Detalles Bibliográficos
Autores principales: Leclerc, Marine, Voilin, Elodie, Gros, Gwendoline, Corgnac, Stéphanie, de Montpréville, Vincent, Validire, Pierre, Bismuth, Georges, Mami-Chouaib, Fathia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659631/
https://www.ncbi.nlm.nih.gov/pubmed/31350404
http://dx.doi.org/10.1038/s41467-019-11280-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659631/
https://www.ncbi.nlm.nih.gov/pubmed/31350404
http://dx.doi.org/10.1038/s41467-019-11280-z

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