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Single cell analysis of human foetal liver captures the transcriptional profile of hepatobiliary hybrid progenitors

The liver parenchyma is composed of hepatocytes and bile duct epithelial cells (BECs). Controversy exists regarding the cellular origin of human liver parenchymal tissue generation during embryonic development, homeostasis or repair. Here we report the existence of a hepatobiliary hybrid progenitor...

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Detalles Bibliográficos
Autores principales: Segal, Joe M., Kent, Deniz, Wesche, Daniel J., Ng, Soon Seng, Serra, Maria, Oulès, Bénédicte, Kar, Gozde, Emerton, Guy, Blackford, Samuel J. I., Darmanis, Spyros, Miquel, Rosa, Luong, Tu Vinh, Yamamoto, Ryo, Bonham, Andrew, Jassem, Wayel, Heaton, Nigel, Vigilante, Alessandra, King, Aileen, Sancho, Rocio, Teichmann, Sarah, Quake, Stephen R., Nakauchi, Hiromitsu, Rashid, S. Tamir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659636/
https://www.ncbi.nlm.nih.gov/pubmed/31350390
http://dx.doi.org/10.1038/s41467-019-11266-x