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The Henna pigment Lawsone activates the Aryl Hydrocarbon Receptor and impacts skin homeostasis

As a first host barrier, the skin is constantly exposed to environmental insults that perturb its integrity. Tight regulation of skin homeostasis is largely controlled by the aryl hydrocarbon receptor (AhR). Here, we demonstrate that Henna and its major pigment, the naphthoquinone Lawsone activate A...

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Detalles Bibliográficos
Autores principales: Lozza, Laura, Moura-Alves, Pedro, Domaszewska, Teresa, Lage Crespo, Carolina, Streata, Ioana, Kreuchwig, Annika, Puyskens, Andreas, Bechtle, Marina, Klemm, Marion, Zedler, Ulrike, Silviu Ungureanu, Bogdan, Guhlich-Bornhof, Ute, Koehler, Anne-Britta, Stäber, Manuela, Mollenkopf, Hans-Joachim, Hurwitz, Robert, Furkert, Jens, Krause, Gerd, Weiner, January, Jacinto, António, Mihai, Ioana, Leite-de-Moraes, Maria, Siebenhaar, Frank, Maurer, Marcus, Kaufmann, Stefan H. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659674/
https://www.ncbi.nlm.nih.gov/pubmed/31350436
http://dx.doi.org/10.1038/s41598-019-47350-x