Genetic comparison of sickle cell anaemia cohorts from Brazil and the United States reveals high levels of divergence

Genetic analysis of admixed populations raises special concerns with regard to study design and data processing, particularly to avoid population stratification biases. The point mutation responsible for sickle cell anaemia codes for a variant hemoglobin, sickle hemoglobin or HbS, whose presence dri...

Descripción completa

Detalles Bibliográficos
Autores principales: Cruz, Pedro R. S., Ananina, Galina, Gil-da-Silva-Lopes, Vera Lucia, Simioni, Milena, Menaa, Farid, Bezerra, Marcos A. C., Domingos, Igor F., Araújo, Aderson S., Pellegrino, Renata, Hakonarson, Hakon, Costa, Fernando F., de Melo, Mônica Barbosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659681/
https://www.ncbi.nlm.nih.gov/pubmed/31350437
http://dx.doi.org/10.1038/s41598-019-47313-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659681/
https://www.ncbi.nlm.nih.gov/pubmed/31350437
http://dx.doi.org/10.1038/s41598-019-47313-2

Ejemplares similares