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BAM8-22 and its receptor MRGPRX1 may attribute to cholestatic pruritus
Pruritus is an unexpected symptom observed in cholestasis and its mechanism is still unclear. Here, we show that bovine adrenal medulla (BAM) 8–22, an endogenous itch-inducing peptide, could be involved in cholestatic pruritus. It was found that bile duct ligation (BDL) mice, an obstructive cholesta...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659683/ https://www.ncbi.nlm.nih.gov/pubmed/31350433 http://dx.doi.org/10.1038/s41598-019-47267-5 |