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Tear Fluid Pharmacokinetics Following Oral Prednisone Administration in Dogs With and Without Conjunctivitis

Purpose: To describe the pharmacokinetics (PK) of prednisone and prednisolone in tear fluid of dogs receiving oral prednisone at anti-inflammatory to immunosuppressive doses and to assess the impact of induced conjunctivitis on lacrimal drug levels. Methods: Six healthy Beagle dogs were administered...

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Detalles Bibliográficos
Autores principales: Sebbag, Lionel, Yan, Yuqi, Smith, Joe S., Allbaugh, Rachel A., Wulf, Larry W., Mochel, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659750/
https://www.ncbi.nlm.nih.gov/pubmed/31070497
http://dx.doi.org/10.1089/jop.2019.0020