Cargando…

Tear Fluid Pharmacokinetics Following Oral Prednisone Administration in Dogs With and Without Conjunctivitis

Purpose: To describe the pharmacokinetics (PK) of prednisone and prednisolone in tear fluid of dogs receiving oral prednisone at anti-inflammatory to immunosuppressive doses and to assess the impact of induced conjunctivitis on lacrimal drug levels. Methods: Six healthy Beagle dogs were administered...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sebbag, Lionel, Yan, Yuqi, Smith, Joe S., Allbaugh, Rachel A., Wulf, Larry W., Mochel, Jonathan P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mary Ann Liebert, Inc., publishers 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659750/ https://www.ncbi.nlm.nih.gov/pubmed/31070497 http://dx.doi.org/10.1089/jop.2019.0020

Ejemplares similares

Histamine-Induced Conjunctivitis and Breakdown of Blood–Tear Barrier in Dogs: A Model for Ocular Pharmacology and Therapeutics
por: Sebbag, Lionel, et al.
Publicado: (2019)

Tear Film Pharmacokinetics and Systemic Absorption Following Topical Administration of 1% Prednisolone Acetate Ophthalmic Suspension in Dogs
por: Sebbag, Lionel, et al.
Publicado: (2020)

Kinetics and minimal inhibitory concentrations of ceftiofur in tear film following extended-release parenteral administration (Excede(®)) in dogs
por: Bowden, Anna Catherine, et al.
Publicado: (2022)

Pharmacokinetics of Oral Prednisone at Various Doses in Dogs: Preliminary Findings Using a Naïve Pooled-Data Approach
por: Sebbag, Lionel, et al.
Publicado: (2020)

Kinetics of Fluorescein in Tear Film After Eye Drop Instillation in Beagle Dogs: Does Size Really Matter?
por: Sebbag, Lionel, et al.
Publicado: (2019)

Fluorophotometric Assessment of Tear Volume and Turnover Rate in Healthy Dogs and Cats
por: Sebbag, Lionel, et al.
Publicado: (2019)

Impact of Flow Rate, Collection Devices, and Extraction Methods on Tear Concentrations Following Oral Administration of Doxycycline in Dogs and Cats
por: Sebbag, Lionel, et al.
Publicado: (2018)

Prevalence and Antibiotic Susceptibility of Bacterial Isolates From Dogs With Ulcerative Keratitis in Midwestern United States
por: Hewitt, Joshua S., et al.
Publicado: (2020)

Effect of tear collection on lacrimal total protein content in dogs and cats: a comparison between Schirmer strips and ophthalmic sponges
por: Sebbag, Lionel, et al.
Publicado: (2018)

Impact of multi-drug resistance on clinical outcomes of dogs with corneal ulcers infected with Staphylococcus pseudintermedius
por: Mauer, Ashley N., et al.
Publicado: (2022)

Albumin Levels in Tear Film Modulate the Bioavailability of Medically-Relevant Topical Drugs
por: Sebbag, Lionel, et al.
Publicado: (2020)

Pharmacokinetics and Tissue Levels of Pantoprazole in Neonatal Calves After Intravenous Administration
por: Olivarez, Jeff D., et al.
Publicado: (2020)

Albumin in Tears Modulates Bacterial Susceptibility to Topical Antibiotics in Ophthalmology
por: Sebbag, Lionel, et al.
Publicado: (2021)

Clinicopathologic and gastrointestinal effects of administration of prednisone, prednisone with omeprazole, or prednisone with probiotics to dogs: A double‐blind randomized trial
por: Rak, Mariola B., et al.
Publicado: (2023)

Case Report: Successful Management of Refractory Keratomycosis in an Alpaca Using Penetrating Keratoplasty and Combination Antifungal Therapy (Caspofungin 0.5% and Terbinafine 1%)
por: Foote, Braidee C., et al.
Publicado: (2021)

Culture and characterization of canine and feline corneal epithelial organoids: A new tool for the study and treatment of corneal diseases
por: Bedos, Leila, et al.
Publicado: (2022)

Effects of Oral Prednisone Administration on Serum Cystatin C in Dogs
por: Muñoz, J., et al.
Publicado: (2017)

Effect of topical nitric oxide donors 0.03% nitroglycerin and 0.1% hydralazine on intraocular pressure in healthy canine eyes
por: Wilcox, Parker A., et al.
Publicado: (2022)

Pharmacokinetic Exposures Associated With Oral Administration of Sorafenib in Dogs With Spontaneous Tumors
por: Cawley, Jacob R., et al.
Publicado: (2022)

Bacterial Cross-Contamination in a Veterinary Ophthalmology Setting
por: Gentile, Dominic, et al.
Publicado: (2020)

Utility of systemic voriconazole in equine keratomycosis based on pharmacokinetic‐pharmacodynamic analysis of tear fluid following oral administration
por: Tamura, Norihisa, et al.
Publicado: (2020)

Effects of clopidogrel and prednisone on platelet function in healthy dogs
por: Thomason, John, et al.
Publicado: (2020)

Perception and usage of short-term prednisone and prednisolone in dogs
por: Gober, Margaret, et al.
Publicado: (2023)

Viral shedding in tears of COVID-19 cases presenting as conjunctivitis
por: Goel, Ruchi, et al.
Publicado: (2020)

Anticoagulant effects of rivaroxaban, prednisone, alone and in combination, in healthy dogs
por: Hafner, Paige M., et al.
Publicado: (2022)

Granular Conjunctivitis with and without Pannus
por: Cheatham, W.
Publicado: (1887)

Virus recovery from idiopathic conjunctivitis of dogs
Publicado: (2011)

Clinical, clinicopathologic, and gastrointestinal changes from administration of clopidogrel, prednisone, or combination in healthy dogs: A double‐blind randomized trial
por: Whittemore, Jacqueline C., et al.
Publicado: (2019)

Pharmacokinetics of BMEDA after Intravenous Administration in Beagle Dogs
por: Chang, Chih-Hsien, et al.
Publicado: (2014)

Effects of Aspirin and Prednisone on Platelet Function and Thromboxane Synthesis in Healthy Dogs
por: Thomason, John M., et al.
Publicado: (2019)

Comparative Pharmacokinetics of Meloxicam Between Healthy Post-partum vs. Mid-lactation Dairy Cattle
por: Warner, Rochelle, et al.
Publicado: (2020)

Metastatic intraocular hemangiopericytoma in a dog
por: Pucket, Jonathan D., et al.
Publicado: (2017)

Corrigendum: Comparative Pharmacokinetics of Meloxicam Between Healthy Post-partum vs. Mid-lactation Dairy Cattle
por: Warner, Rochelle, et al.
Publicado: (2021)

Tear levels of neuropeptides increase after specific allergen challenge in allergic conjunctivitis
por: Sacchetti, Marta, et al.
Publicado: (2011)

In vitro Cytotoxicity and Pharmacokinetic Evaluation of Pharmacological Ascorbate in Dogs
por: Musser, Margaret L., et al.
Publicado: (2019)

Successful management of 3 dogs with colonic pythiosis using itraconzaole, terbinafine, and prednisone
por: Reagan, Krystle L., et al.
Publicado: (2019)

Pharmacokinetics of Single‐Dose Rectal Zonisamide Administration in Normal Dogs
por: Brewer, D.M., et al.
Publicado: (2015)

Pharmacokinetics of esomeprazole following intravenous and oral administration in healthy dogs
por: Cook, Emily K, et al.
Publicado: (2016)

Pharmacokinetics of enflicoxib in dogs: Effects of prandial state and repeated administration
por: Homedes, Josep, et al.
Publicado: (2021)

Pharmacokinetics of Pantoprazole and Pantoprazole Sulfone in Goats After Intravenous Administration: A Preliminary Report
por: Smith, Joe S., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_tieohmhqdmc7a5hjig82cibdgv