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HNRNPA1-mediated 3′ UTR length changes of HN1 contributes to cancer- and senescence-associated phenotypes

Cellular senescence has been regarded as a mechanism of tumor suppression. Studying the regulation of gene expression at various levels in cell senescence will shed light on cancer therapy. Alternative polyadenylation (APA) regulates gene expression by altering 3′ untranslated regions (3′ UTR) and p...

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Detalles Bibliográficos
Autores principales: Jia, Qi, Nie, Hongbo, Yu, Peng, Xie, Baiyun, Wang, Chenji, Yang, Fu, Wei, Gang, Ni, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660030/
https://www.ncbi.nlm.nih.gov/pubmed/31257225
http://dx.doi.org/10.18632/aging.102060