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Assessment of ERBB2 and TOP2α gene status and expression profile in feline mammary tumors: findings and guidelines

In humans, the ERBB2 gene amplification and overexpression are biomarkers for invasive breast cancer and a therapeutic target. Also, TOP2α gene aberrations predict the response to anthracycline-based adjuvant chemotherapy. Although feline mammary tumors (FMTs) are good models in comparative oncology...

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Detalles Bibliográficos
Autores principales: Ferreira, Daniela, Soares, Maria, Correia, Jorge, Adega, Filomena, Ferreira, Fernando, Chaves, Raquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660035/
https://www.ncbi.nlm.nih.gov/pubmed/31301170
http://dx.doi.org/10.18632/aging.102079