Spontaneous γH2AX foci in human dermal fibroblasts in relation to proliferation activity and aging

We assessed the effects of donor age on clonogenicity, proliferative potential, and spontaneous γH2AX foci in the proliferating (Ki67 +) and senescent (SA β-gal +) cultures of skin fibroblasts isolated from 34 donors of different age (23-82 years). Here, we demonstrated that neither the colony formi...

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Detalles Bibliográficos
Autores principales: Zorin, Vadim, Grekhova, Anna, Pustovalova, Margarita, Zorina, Alla, Smetanina, Nadezhda, Vorobyeva, Natalia, Kopnin, Pavel, Gilmutdinova, Ilmira, Moskalev, Alexey, Osipov, Andreyan N., Leonov, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660037/
https://www.ncbi.nlm.nih.gov/pubmed/31289256
http://dx.doi.org/10.18632/aging.102067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660037/
https://www.ncbi.nlm.nih.gov/pubmed/31289256
http://dx.doi.org/10.18632/aging.102067

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