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Spontaneous γH2AX foci in human dermal fibroblasts in relation to proliferation activity and aging
We assessed the effects of donor age on clonogenicity, proliferative potential, and spontaneous γH2AX foci in the proliferating (Ki67 +) and senescent (SA β-gal +) cultures of skin fibroblasts isolated from 34 donors of different age (23-82 years). Here, we demonstrated that neither the colony formi...
Autores principales: | Zorin, Vadim, Grekhova, Anna, Pustovalova, Margarita, Zorina, Alla, Smetanina, Nadezhda, Vorobyeva, Natalia, Kopnin, Pavel, Gilmutdinova, Ilmira, Moskalev, Alexey, Osipov, Andreyan N., Leonov, Sergey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660037/ https://www.ncbi.nlm.nih.gov/pubmed/31289256 http://dx.doi.org/10.18632/aging.102067 |
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