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Ammonia induces calpain-dependent cleavage of CRMP-2 during neurite degeneration in primary cultured neurons
Hyperammonemia in the CNS induces irreversible damages to neurons due to ultimate cell loss. Neurite degeneration, a primary event that leads to neuronal cell death, remains less elucidated especially in hyperammonemia circumstances. Here, we found that the administration of ammonia induced neurite...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660054/ https://www.ncbi.nlm.nih.gov/pubmed/31278888 http://dx.doi.org/10.18632/aging.102053 |