Ammonia induces calpain-dependent cleavage of CRMP-2 during neurite degeneration in primary cultured neurons

Hyperammonemia in the CNS induces irreversible damages to neurons due to ultimate cell loss. Neurite degeneration, a primary event that leads to neuronal cell death, remains less elucidated especially in hyperammonemia circumstances. Here, we found that the administration of ammonia induced neurite...

Descripción completa

Detalles Bibliográficos
Autores principales: Cai, Zhenbin, Zhu, Xiaonan, Zhang, Guowei, Wu, Fengming, Lin, Hongsheng, Tan, Minghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660054/
https://www.ncbi.nlm.nih.gov/pubmed/31278888
http://dx.doi.org/10.18632/aging.102053

Ejemplares similares

Ejemplares similares