Quantification of Double Stranded DNA Breaks and Telomere Length as Proxies for Corneal Damage and Replicative Stress in Human Keratoconus Corneas

PURPOSE: The pathogenesis of keratoconus (KC) is multifactorial, and associated with oxidative stress and subsequent DNA damage. We investigate differences in DNA damage and replicative stress in patients with KC, and in healthy and diseased controls. METHODS: We obtained 64 corneal buttons from 27...

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Detalles Bibliográficos
Autores principales: Wisse, Robert P. L., Kuiper, Jonas J. W., Radstake, Timothy R. D., Broen, Jasper C. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660185/
https://www.ncbi.nlm.nih.gov/pubmed/31372311
http://dx.doi.org/10.1167/tvst.8.4.10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660185/
https://www.ncbi.nlm.nih.gov/pubmed/31372311
http://dx.doi.org/10.1167/tvst.8.4.10

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