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Trans-toxin ion-sensitivity of charybdotoxin-blocked potassium-channels reveals unbinding transitional states

In silico and in vitro studies have made progress in understanding protein–protein complex formation; however, the molecular mechanisms for their dissociation are unclear. Protein–protein complexes, lasting from microseconds to years, often involve induced-fit, challenging computational or kinetic a...

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Detalles Bibliográficos
Autores principales: Moldenhauer, Hans, Díaz-Franulic, Ignacio, Poblete, Horacio, Naranjo, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660193/
https://www.ncbi.nlm.nih.gov/pubmed/31271355
http://dx.doi.org/10.7554/eLife.46170