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Genome-Wide DNA Methylation Analysis Reveals Epigenetic Pattern of SH2B1 in Chinese Monozygotic Twins Discordant for Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder. Aberrant DNA methylation has been observed in ASD but the mechanisms remain largely unknown. Here, we employed discordant monozygotic twins to investigate the contribution of DNA methylation to ASD etiology. Genome-wide DNA met...

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Detalles Bibliográficos
Autores principales: Liang, Shuang, Li, Zhenzhi, Wang, Yihan, Li, Xiaodan, Yang, Xiaolei, Zhan, Xiaolei, Huang, Yan, Gao, Zhaomin, Zhang, Min, Sun, Caihong, Zhang, Yan, Wu, Lijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660254/
https://www.ncbi.nlm.nih.gov/pubmed/31379474
http://dx.doi.org/10.3389/fnins.2019.00712