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Fungal Kinases With a Sweet Tooth: Pleiotropic Roles of Their Phosphorylated Inositol Sugar Products in the Pathogenicity of Cryptococcus neoformans Present Novel Drug Targeting Opportunities

Invasive fungal pathogens cause more than 300 million serious human infections and 1.6 million deaths per year. A clearer understanding of the mechanisms by which these fungi cause disease is needed to identify novel targets for urgently needed therapies. Kinases are key components of the signaling...

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Detalles Bibliográficos
Autores principales: Lev, Sophie, Li, Cecilia, Desmarini, Desmarini, Sorrell, Tania C., Saiardi, Adolfo, Djordjevic, Julianne T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660261/
https://www.ncbi.nlm.nih.gov/pubmed/31380293
http://dx.doi.org/10.3389/fcimb.2019.00248