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Fungal Kinases With a Sweet Tooth: Pleiotropic Roles of Their Phosphorylated Inositol Sugar Products in the Pathogenicity of Cryptococcus neoformans Present Novel Drug Targeting Opportunities
Invasive fungal pathogens cause more than 300 million serious human infections and 1.6 million deaths per year. A clearer understanding of the mechanisms by which these fungi cause disease is needed to identify novel targets for urgently needed therapies. Kinases are key components of the signaling...
Autores principales: | Lev, Sophie, Li, Cecilia, Desmarini, Desmarini, Sorrell, Tania C., Saiardi, Adolfo, Djordjevic, Julianne T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660261/ https://www.ncbi.nlm.nih.gov/pubmed/31380293 http://dx.doi.org/10.3389/fcimb.2019.00248 |
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