An Orphan CpG Island Drives Expression of a let-7 miRNA Precursor with an Important Role in Mouse Development

Most human genes are associated with promoters embedded in non-methylated, G + C-rich CpG islands (CGIs). Not all CGIs are found at annotated promoters, however, raising the possibility that many serve as promoters for transcripts that do not code for proteins. To test this hypothesis, we searched f...

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Detalles Bibliográficos
Autores principales: Koerner, Martha V., Chhatbar, Kashyap, Webb, Shaun, Cholewa-Waclaw, Justyna, Selfridge, Jim, De Sousa, Dina, Skarnes, Bill, Rosen, Barry, Thomas, Mark, Bottomley, Joanna, Ramirez-Solis, Ramiro, Lelliott, Christopher, Adams, David J., Bird, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660310/
https://www.ncbi.nlm.nih.gov/pubmed/31354981
http://dx.doi.org/10.3390/epigenomes3010007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660310/
https://www.ncbi.nlm.nih.gov/pubmed/31354981
http://dx.doi.org/10.3390/epigenomes3010007

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