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EDTA Treatment for Overcoming the Prozone Effect and for Predicting C1q Binding in HLA Antibody Testing

The Luminex-based single antigen bead (SAB) assay is widely used to detect HLA antibody in transplant recipients. However, one limitation of the SAB assay is the prozone effect, which occurs mostly as a result of complement interference. We investigated the efficacy of EDTA treatment for overcoming...

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Detalles Bibliográficos
Autores principales: Kim, Hoon Seok, Choi, Ae-Ran, Yang, Mina, Oh, Eun-Jee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Laboratory Medicine 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660344/
https://www.ncbi.nlm.nih.gov/pubmed/31240886
http://dx.doi.org/10.3343/alm.2019.39.6.572