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The role of ABCA7 in Alzheimer’s disease: evidence from genomics, transcriptomics and methylomics
Genome-wide association studies (GWAS) originally identified ATP-binding cassette, sub-family A, member 7 (ABCA7), as a novel risk gene of Alzheimer’s disease (AD). Since then, accumulating evidence from in vitro, in vivo, and human-based studies has corroborated and extended this association, promo...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660495/ https://www.ncbi.nlm.nih.gov/pubmed/30903345 http://dx.doi.org/10.1007/s00401-019-01994-1 |