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The role of ABCA7 in Alzheimer’s disease: evidence from genomics, transcriptomics and methylomics

Genome-wide association studies (GWAS) originally identified ATP-binding cassette, sub-family A, member 7 (ABCA7), as a novel risk gene of Alzheimer’s disease (AD). Since then, accumulating evidence from in vitro, in vivo, and human-based studies has corroborated and extended this association, promo...

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Detalles Bibliográficos
Autores principales: De Roeck, Arne, Van Broeckhoven, Christine, Sleegers, Kristel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660495/
https://www.ncbi.nlm.nih.gov/pubmed/30903345
http://dx.doi.org/10.1007/s00401-019-01994-1