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Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer’s disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disease in which the formation of extracellular aggregates of amyloid beta (Aβ) peptide, fibrillary tangles of intraneuronal tau and microglial activation are major pathological hallmarks. One of the key molecules involved in microglial act...

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Detalles Bibliográficos
Autores principales: Boza-Serrano, Antonio, Ruiz, Rocío, Sanchez-Varo, Raquel, García-Revilla, Juan, Yang, Yiyi, Jimenez-Ferrer, Itzia, Paulus, Agnes, Wennström, Malin, Vilalta, Anna, Allendorf, David, Davila, Jose Carlos, Stegmayr, John, Jiménez, Sebastian, Roca-Ceballos, Maria A., Navarro-Garrido, Victoria, Swanberg, Maria, Hsieh, Christine L., Real, Luis M., Englund, Elisabet, Linse, Sara, Leffler, Hakon, Nilsson, Ulf J., Brown, Guy C., Gutierrez, Antonia, Vitorica, Javier, Venero, Jose Luis, Deierborg, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660511/
https://www.ncbi.nlm.nih.gov/pubmed/31006066
http://dx.doi.org/10.1007/s00401-019-02013-z