RhoA regulates translation of the Nogo-A decoy SPARC in white matter-invading glioblastomas

Glioblastomas strongly invade the brain by infiltrating into the white matter along myelinated nerve fiber tracts even though the myelin protein Nogo-A prevents cell migration by activating inhibitory RhoA signaling. The mechanisms behind this long-known phenomenon remained elusive so far, precludin...

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Detalles Bibliográficos
Autores principales: Wirthschaft, Peter, Bode, Julia, Soni, Himanshu, Dietrich, Fabio, Krüwel, Thomas, Fischer, Bernd, Knobbe-Thomsen, Christiane B., Rossetti, Giulia, Hentschel, Andreas, Mack, Norman, Schönig, Kai, Breckwoldt, Michael O., Schmandke, André, Pusch, Stefan, Medenbach, Jan, Bendszus, Martin, Schwab, Martin E., von Deimling, Andreas, Kool, Marcel, Herold-Mende, Christel, Reifenberger, Guido, Ahrends, Robert, Tews, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660512/
https://www.ncbi.nlm.nih.gov/pubmed/31062076
http://dx.doi.org/10.1007/s00401-019-02021-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660512/
https://www.ncbi.nlm.nih.gov/pubmed/31062076
http://dx.doi.org/10.1007/s00401-019-02021-z

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