The new genetic landscape of Alzheimer’s disease: from amyloid cascade to genetically driven synaptic failure hypothesis?

A strong genetic predisposition (60–80% of attributable risk) is present in Alzheimer’s disease (AD). In view of this major genetic component, identification of the genetic risk factors has been a major objective in the AD field with the ultimate aim to better understand the pathological processes....

Descripción completa

Detalles Bibliográficos
Autores principales: Dourlen, Pierre, Kilinc, Devrim, Malmanche, Nicolas, Chapuis, Julien, Lambert, Jean-Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660578/
https://www.ncbi.nlm.nih.gov/pubmed/30982098
http://dx.doi.org/10.1007/s00401-019-02004-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660578/
https://www.ncbi.nlm.nih.gov/pubmed/30982098
http://dx.doi.org/10.1007/s00401-019-02004-0

Ejemplares similares