Myosin 1b Regulates Nuclear AKT Activation by Preventing Localization of PTEN in the Nucleus

Insulin-induced AKT activation is dependent on phosphoinositide 3-kinase and opposed by tumor suppressor phosphatase and tensin homolog (PTEN). Our previous study demonstrates that myosin 1b (MYO1B) mediates arginase-II-induced activation of mechanistic target of rapamycin complex 1 that is regulate...

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Detalles Bibliográficos
Autores principales: Yu, Yi, Xiong, Yuyan, Ladeiras, Diogo, Yang, Zhihong, Ming, Xiu-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660601/
https://www.ncbi.nlm.nih.gov/pubmed/31349190
http://dx.doi.org/10.1016/j.isci.2019.07.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660601/
https://www.ncbi.nlm.nih.gov/pubmed/31349190
http://dx.doi.org/10.1016/j.isci.2019.07.010

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