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Myosin 1b Regulates Nuclear AKT Activation by Preventing Localization of PTEN in the Nucleus
Insulin-induced AKT activation is dependent on phosphoinositide 3-kinase and opposed by tumor suppressor phosphatase and tensin homolog (PTEN). Our previous study demonstrates that myosin 1b (MYO1B) mediates arginase-II-induced activation of mechanistic target of rapamycin complex 1 that is regulate...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660601/ https://www.ncbi.nlm.nih.gov/pubmed/31349190 http://dx.doi.org/10.1016/j.isci.2019.07.010 |