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Analysis of the reannealing- instead of melting-curve in the detection of JAK2 V617F mutation by HRM method
BACKGROUND: The Janus kinase 2 (JAK2) has an important role in the intracellular signaling in normal and neoplastic cells. JAK2 mutation, called JAK2 V617F, is frequently found in Philadelphia chromosome-negative myeloproliferative neoplasms. We aimed to assess the analytical efficiency of high-reso...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660628/ https://www.ncbi.nlm.nih.gov/pubmed/31413649 http://dx.doi.org/10.2147/JBM.S204222 |