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Analysis of the reannealing- instead of melting-curve in the detection of JAK2 V617F mutation by HRM method

BACKGROUND: The Janus kinase 2 (JAK2) has an important role in the intracellular signaling in normal and neoplastic cells. JAK2 mutation, called JAK2 V617F, is frequently found in Philadelphia chromosome-negative myeloproliferative neoplasms. We aimed to assess the analytical efficiency of high-reso...

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Detalles Bibliográficos
Autores principales: Moradabadi, Alireza, Fatemi, Ahmad, Noroozi-Aghideh, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660628/
https://www.ncbi.nlm.nih.gov/pubmed/31413649
http://dx.doi.org/10.2147/JBM.S204222