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The acute toxic effects of platinum nanoparticles on ion channels, transmembrane potentials of cardiomyocytes in vitro and heart rhythm in vivo in mice

BACKGROUND: Platinum nanoparticles (PtNPs) have been considered a nontoxic nanomaterial and been clinically used in cancer chemotherapy. PtNPs can also be vehicle exhausts and environmental pollutants. These situations increase the possibility of human exposure to PtNPs. However, the potential bioto...

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Detalles Bibliográficos
Autores principales: Lin, Cai-Xia, Gu, Jing-Li, Cao, Ji-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660630/
https://www.ncbi.nlm.nih.gov/pubmed/31413565
http://dx.doi.org/10.2147/IJN.S209135