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RNA helicase p68 deploys β-catenin in regulating RelA/p65 gene expression: implications in colon cancer

BACKGROUND: RelA/p65 a crucial member of NF-κB signaling pathway plays diverse role in mediating oncogenesis. Limited knowledge prevails on the mechanistic insights of RelA gene regulation. RNA helicase p68 apart from being a vital player of RNA metabolism acts as a transcriptional coactivator of se...

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Detalles Bibliográficos
Autores principales: Khare, Veenita, Tabassum, Shaheda, Chatterjee, Uttara, Chatterjee, Sandip, Ghosh, Mrinal K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660689/
https://www.ncbi.nlm.nih.gov/pubmed/31351496
http://dx.doi.org/10.1186/s13046-019-1304-y