Loss of gut barrier integrity triggers activation of islet-reactive T cells and autoimmune diabetes

Low-grade intestinal inflammation and alterations of gut barrier integrity are found in patients affected by extraintestinal autoimmune diseases such as type 1 diabetes (T1D), but a direct causal link between enteropathy and triggering of autoimmunity is yet to be established. Here, we found that on...

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Detalles Bibliográficos
Autores principales: Sorini, Chiara, Cosorich, Ilaria, Lo Conte, Marta, De Giorgi, Lorena, Facciotti, Federica, Lucianò, Roberta, Rocchi, Martina, Ferrarese, Roberto, Sanvito, Francesca, Canducci, Filippo, Falcone, Marika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660755/
https://www.ncbi.nlm.nih.gov/pubmed/31182588
http://dx.doi.org/10.1073/pnas.1814558116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660755/
https://www.ncbi.nlm.nih.gov/pubmed/31182588
http://dx.doi.org/10.1073/pnas.1814558116

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