Cargando…

Telomere shortening rate predicts species life span

Telomere shortening to a critical length can trigger aging and shorter life spans in mice and humans by a mechanism that involves induction of a persistent DNA damage response at chromosome ends and loss of cellular viability. However, whether telomere length is a universal determinant of species lo...

Descripción completa

Detalles Bibliográficos
Autores principales: Whittemore, Kurt, Vera, Elsa, Martínez-Nevado, Eva, Sanpera, Carola, Blasco, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660761/
https://www.ncbi.nlm.nih.gov/pubmed/31285335
http://dx.doi.org/10.1073/pnas.1902452116