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Telomere shortening rate predicts species life span
Telomere shortening to a critical length can trigger aging and shorter life spans in mice and humans by a mechanism that involves induction of a persistent DNA damage response at chromosome ends and loss of cellular viability. However, whether telomere length is a universal determinant of species lo...
Autores principales: | Whittemore, Kurt, Vera, Elsa, Martínez-Nevado, Eva, Sanpera, Carola, Blasco, Maria A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660761/ https://www.ncbi.nlm.nih.gov/pubmed/31285335 http://dx.doi.org/10.1073/pnas.1902452116 |
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