Quantitative modelling predicts the impact of DNA methylation on RNA polymerase II traffic

Patterns of gene expression are primarily determined by proteins that locally enhance or repress transcription. While many transcription factors target a restricted number of genes, others appear to modulate transcription levels globally. An example is MeCP2, an abundant methylated-DNA binding prote...

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Detalles Bibliográficos
Autores principales: Cholewa-Waclaw, Justyna, Shah, Ruth, Webb, Shaun, Chhatbar, Kashyap, Ramsahoye, Bernard, Pusch, Oliver, Yu, Miao, Greulich, Philip, Waclaw, Bartlomiej, Bird, Adrian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660794/
https://www.ncbi.nlm.nih.gov/pubmed/31289233
http://dx.doi.org/10.1073/pnas.1903549116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660794/
https://www.ncbi.nlm.nih.gov/pubmed/31289233
http://dx.doi.org/10.1073/pnas.1903549116

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