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Quantitative modelling predicts the impact of DNA methylation on RNA polymerase II traffic
Patterns of gene expression are primarily determined by proteins that locally enhance or repress transcription. While many transcription factors target a restricted number of genes, others appear to modulate transcription levels globally. An example is MeCP2, an abundant methylated-DNA binding prote...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660794/ https://www.ncbi.nlm.nih.gov/pubmed/31289233 http://dx.doi.org/10.1073/pnas.1903549116 |