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Promoter conservation in HDACs points to functional implications

BACKGROUND: Histone deacetylases (HDACs) are the proteins responsible for removing the acetyl group from lysine residues of core histones in chromosomes, a crucial component of gene regulation. Eleven known HDACs exist in humans and most other vertebrates. While the basic function of HDACs has been...

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Detalles Bibliográficos
Autores principales: Boltz, Toni A., Khuri, Sawsan, Wuchty, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660948/
https://www.ncbi.nlm.nih.gov/pubmed/31351464
http://dx.doi.org/10.1186/s12864-019-5973-x