Combined inhibition of Aurora A and p21-activated kinase 1 as a new treatment strategy in breast cancer

PURPOSE: The serine-threonine kinases Aurora A (AURKA) and p21-activated kinase 1 (PAK1) are frequently overexpressed in breast tumors, with overexpression promoting aggressive breast cancer phenotypes and poor clinical outcomes. Besides the well-defined roles of these proteins in control of cell di...

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Detalles Bibliográficos
Autores principales: Korobeynikov, Vladislav, Borakove, Michelle, Feng, Yayi, Wuest, William M., Koval, Alex B., Nikonova, Anna S., Serebriiskii, Ilya, Chernoff, Jonathan, Borges, Virginia F., Golemis, Erica A., Shagisultanova, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Preclinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661032/
https://www.ncbi.nlm.nih.gov/pubmed/31254157
http://dx.doi.org/10.1007/s10549-019-05329-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661032/
https://www.ncbi.nlm.nih.gov/pubmed/31254157
http://dx.doi.org/10.1007/s10549-019-05329-2

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