Do clinical trials truly mirror their target population? An external validity analysis of national register versus trial data from the Swedish prospective SENOMIC trial on sentinel node micrometastases in breast cancer

PURPOSE: Increasing evidence suggests that completion axillary lymph node dissection (ALND) may be omitted in breast cancer patients with limited axillary nodal metastases. However, the representativeness of trial participants for the original clinical practice population, and thus, the generalizabi...

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Detalles Bibliográficos
Autores principales: Andersson, Y., Bergkvist, L., Frisell, J., de Boniface, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Clinical Trial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661061/
https://www.ncbi.nlm.nih.gov/pubmed/31236811
http://dx.doi.org/10.1007/s10549-019-05328-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661061/
https://www.ncbi.nlm.nih.gov/pubmed/31236811
http://dx.doi.org/10.1007/s10549-019-05328-3

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