Genipin induces mitochondrial dysfunction and apoptosis via downregulation of Stat3/mcl-1 pathway in gastric cancer

BACKGROUND: Genipin is a compound derived from gardenia fruit extract. Although Genipin has anti-tumor effects in various cancers, its effect and mechanism in gastric cancer remain unclear. Here, we investigated the relationship between the anticancer effect of Genipin and signal transducer and acti...

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Detalles Bibliográficos
Autores principales: Jo, Min Jee, Jeong, Soyeon, Yun, Hye Kyeong, Kim, Dae Yeong, Kim, Bo Ram, Kim, Jung Lim, Na, Yoo Jin, Park, Seong Hye, Jeong, Yoon A., Kim, Bu Gyeom, Ashktorab, Hassan, Smoot, Duane T., Heo, Jun Young, Han, Jeongsu, Lee, Dae-Hee, Oh, Sang Cheul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661087/
https://www.ncbi.nlm.nih.gov/pubmed/31351462
http://dx.doi.org/10.1186/s12885-019-5957-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661087/
https://www.ncbi.nlm.nih.gov/pubmed/31351462
http://dx.doi.org/10.1186/s12885-019-5957-x

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