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A multi-labeled tree dissimilarity measure for comparing “clonal trees” of tumor progression

We introduce a new dissimilarity measure between a pair of “clonal trees”, each representing the progression and mutational heterogeneity of a tumor sample, constructed by the use of single cell or bulk high throughput sequencing data. In a clonal tree, each vertex represents a specific tumor clone,...

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Detalles Bibliográficos
Autores principales: Karpov, Nikolai, Malikic, Salem, Rahman, Md. Khaledur, Sahinalp, S. Cenk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661107/
https://www.ncbi.nlm.nih.gov/pubmed/31372179
http://dx.doi.org/10.1186/s13015-019-0152-9