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circNrxn2 Promoted WAT Browning via Sponging miR-103 to Relieve Its Inhibition of FGF10 in HFD Mice

The accumulation of excess white adipose tissue (WAT) has harmful consequences on metabolic health. WAT browning confers beneficial effects on adiposity, insulin resistance, and hyperlipidemia. In this study, it was found out that circNrxn2 sponged miR-103 and enhanced FGF10 levels in HFD mice WAT....

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Detalles Bibliográficos
Autores principales: Zhang, Tiantian, Zhang, Zhenzhen, Xia, Tianyu, Liu, Chenlong, Sun, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661467/
https://www.ncbi.nlm.nih.gov/pubmed/31362242
http://dx.doi.org/10.1016/j.omtn.2019.06.019