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Profibrotic effects of angiotensin II and transforming growth factor beta on feline kidney epithelial cells

OBJECTIVES: The aim of this study was to evaluate the role of angiotensin II (AT-II) and its main mediator, transforming growth factor beta 1 (TGF-β1), in the development of feline renal fibrosis. METHODS: Expression of marker genes indicating epithelial-to-mesenchymal transition (EMT), profibrotic...

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Detalles Bibliográficos
Autores principales: van Beusekom, Cyrina D, Zimmering, Tanja M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661713/
https://www.ncbi.nlm.nih.gov/pubmed/30345862
http://dx.doi.org/10.1177/1098612X18805862