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Novel LC–MS/MS method for analysis of metformin and canagliflozin in human plasma: application to a pharmacokinetic study

Highly sensitive and selective liquid chromatography/tandem mass spectrometry (LC–MS/MS) method was developed and validated for the simultaneous estimation of the recently approved oral hypoglycemic mixture; metformin (MET) and canagliflozin (CFZ) in human plasma using propranolol HCl (PPL) and tada...

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Detalles Bibliográficos
Autores principales: Mohamed, Dalia, Elshahed, Mona S., Nasr, Tamer, Aboutaleb, Nageh, Zakaria, Ola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661773/
https://www.ncbi.nlm.nih.gov/pubmed/31384829
http://dx.doi.org/10.1186/s13065-019-0597-4