In silico design and synthesis of targeted rutin derivatives as xanthine oxidase inhibitors

BACKGROUND: Xanthine oxidase is an important enzyme of purine catabolism pathway and has been associated directly in pathogenesis of gout and indirectly in many pathological conditions like cancer, diabetes and metabolic syndrome. In this research rutin, a bioactive flavonoid was explored to determi...

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Detalles Bibliográficos
Autores principales: Malik, Neelam, Dhiman, Priyanka, Khatkar, Anurag
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661775/
https://www.ncbi.nlm.nih.gov/pubmed/31384818
http://dx.doi.org/10.1186/s13065-019-0585-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661775/
https://www.ncbi.nlm.nih.gov/pubmed/31384818
http://dx.doi.org/10.1186/s13065-019-0585-8

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