Synthesis, biological activity and molecular docking of new tricyclic series as α-glucosidase inhibitors

Diabetes is an emerging metabolic disorder. α-Glucosidase inhibitors, such as acarbose, delay the hydrolysis of carbohydrates by interfering with the digestive enzymes. This action decreases the glucose absorption and the postprandial glucose level. We have synthesized 25 tricyclic 2-phenoxypyrido[3...

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Detalles Bibliográficos
Autores principales: Abuelizz, Hatem A., Iwana, Nor Azman N. I., Ahmad, Rohaya, Anouar, El-Hassane, Marzouk, Mohamed, Al-Salahi, Rashad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661812/
https://www.ncbi.nlm.nih.gov/pubmed/31384800
http://dx.doi.org/10.1186/s13065-019-0560-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661812/
https://www.ncbi.nlm.nih.gov/pubmed/31384800
http://dx.doi.org/10.1186/s13065-019-0560-4

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