Design, synthesis and evaluation of novel 3,5-disubstituted benzamide derivatives as allosteric glucokinase activators

Glucokinase (GK) is the key enzyme expressed in β-cells of pancreas and liver hepatocytes and helps in the maintenance of blood glucose levels in normal range. Activators of GK are the novel category of drug candidates which activate GK enzyme allosterically and show their antidiabetic activity. A n...

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Detalles Bibliográficos
Autores principales: Grewal, Ajmer Singh, Kharb, Rajeev, Prasad, Deo Nandan, Dua, Jagdeep Singh, Lather, Viney
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661843/
https://www.ncbi.nlm.nih.gov/pubmed/31384754
http://dx.doi.org/10.1186/s13065-019-0532-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661843/
https://www.ncbi.nlm.nih.gov/pubmed/31384754
http://dx.doi.org/10.1186/s13065-019-0532-8

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