Translation of Diverse Aramid- and 1,3-Dicarbonyl-peptides by Wild Type Ribosomes in Vitro

[Image: see text] Here, we report that wild type Escherichia coli ribosomes accept and elongate precharged initiator tRNAs acylated with multiple benzoic acids, including aramid precursors, as well as malonyl (1,3-dicarbonyl) substrates to generate a diverse set of aramid-peptide and polyketide-pept...

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Detalles Bibliográficos
Autores principales: Ad, Omer, Hoffman, Kyle S., Cairns, Andrew G., Featherston, Aaron L., Miller, Scott J., Söll, Dieter, Schepartz, Alanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661870/
https://www.ncbi.nlm.nih.gov/pubmed/31403077
http://dx.doi.org/10.1021/acscentsci.9b00460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661870/
https://www.ncbi.nlm.nih.gov/pubmed/31403077
http://dx.doi.org/10.1021/acscentsci.9b00460

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